IFNG, interferon gamma, 3458

N. diseases: 1519; N. variants: 11
Disease: Histoplasmosis ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0019655
Disease: Histoplasmosis
Histoplasmosis 		0.010 Biomarker disease BEFREE Genetic defects in the interferon-gamma (IFN-γ)/STAT1 signaling pathway, CD40/CD40 ligand- and IL12/IL12-receptor-mediated crosstalk between phagocytes and T-cells, and STAT3-mediated Th17 differentiation have been reported in HIV-negative children with talaromycosis and other endemic mycoses such as histoplasmosis, coccidioidomycosis, and paracoccidioidomycosis. 31572394 2019