Disease: Cystic Fibrosis ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0010674
Disease: Cystic Fibrosis
Cystic Fibrosis 		0.030 GeneticVariation disease BEFREE These results showed the association of the IFRD1-rs7817 polymorphism with NP in CF patients. 26397160 2015
CUI: C0010674
Disease: Cystic Fibrosis
Cystic Fibrosis 		0.030 AlteredExpression disease BEFREE In vitro regulation studies showed that CF airway fluid and the CF-characteristic chemokines CXCL8 and CXCL2 down-regulated IFRD1 expression in neutrophils, an effect that was mediated through CXCR2. 23043087 2013
CUI: C0010674
Disease: Cystic Fibrosis
Cystic Fibrosis 		0.030 Biomarker disease BEFREE 12-O-tetradecanoyl phorbol-13-acetate-induced sequence 7/interferon related development regulator 1 (Tis7/IFRD1) has been recently identified as a modifier gene in lung inflammatory disease severity in patients with cystic fibrosis (CF), based upon its capacity to regulate inflammatory activities in neutrophils. 21723850 2011