|
Dyslipidemias
|
0.400 |
GeneticVariation
|
group |
BEFREE |
To better inform prevention, future consideration should be given toward managing dyslipidemia in women carrying the APOE ɛ4 allele.
|
30689578 |
2019 |
|
Dyslipidemias
|
0.400 |
GeneticVariation
|
group |
BEFREE |
ApoE4 allele is associated with obesity independent of dyslipidemia in women but not men with a family history of diabetes.
|
11553047 |
2001 |
|
Dyslipidemias
|
0.400 |
GeneticVariation
|
group |
BEFREE |
A similar phenotype of combined dyslipidemia was induced in apoE(-/-) or apoE(-/-) x LDLr(-/-) mice after infection with a low dose (4 x 10(8) pfu) of an adenovirus expressing the apoE4[R142V/R145V] mutant previously shown to be defective in receptor binding.
|
16339113 |
2006 |
|
Dyslipidemias
|
0.400 |
GeneticVariation
|
group |
BEFREE |
Further screening for common apoE gene variants in individuals at risk for dyslipidemia may reveal abnormal heteroduplex patterns and uncover further mutations in this important lipid-regulating gene.
|
15514092 |
2005 |
|
Dyslipidemias
|
0.400 |
GeneticVariation
|
group |
BEFREE |
APOE genotypes are associated with lipid levels in patients with RA, and may contribute to dyslipidemia in some patients.
|
23613766 |
2013 |
|
Dyslipidemias
|
0.400 |
GeneticVariation
|
group |
BEFREE |
Dyslipidemia and apolipoprotein E4 (APOE ϵ4) allele are risk factors for age-related cognitive decline, but how these risks are modified by human immunodeficiency virus (HIV) infection is unclear.
|
27448678 |
2016 |
|
Dyslipidemias
|
0.400 |
GeneticVariation
|
group |
BEFREE |
Polymorphisms of the ApoE (Apolipoprotein E) gene and their influence on dyslipidemia in HIV-1-infected individuals.
|
25420659 |
2015 |
|
Dyslipidemias
|
0.400 |
GeneticVariation
|
group |
BEFREE |
We evaluated the contribution of APOC3 -482C-->T, -455T-->C, and 3238C-->G; epsilon 2 and epsilon 4 alleles of APOE; and TNF -238G-->A to dyslipidemia and lipoatrophy by longitudinally modeling >2600 lipid determinations and 2328 lipoatrophy assessments in 329 ART-treated patients during a median follow-up period of 3.4 years.
|
15809899 |
2005 |
|
Dyslipidemias
|
0.400 |
GeneticVariation
|
group |
BEFREE |
Compared with APOE*3/*3 homozygotes, patients with the APOE*4 allele had 1.3 times higher risk for CAD after ignoring dyslipidemia, but this risk was modified after adjusting for dyslipidemia.
|
17985658 |
2007 |
|
Dyslipidemias
|
0.400 |
GeneticVariation
|
group |
LHGDN |
The objective of this study was to evaluate 1) whether non single nucleotide polymorphisms-coding (non-cSNP) in the apolipoprotein E gene (APOE) identified by resequencing studies contribute to statistically explaining dyslipidemia if variations in the two cSNPs in exon 4 that define the 2, 3, and 4 alleles are ignored, and 2) whether the contribution of these additional SNPs persists when variations in the cSNPs are considered.
|
16317171 |
2006 |
|
Dyslipidemias
|
0.400 |
GeneticVariation
|
group |
BEFREE |
The APOE p.Leu167del mutation was also found in the proband's son and granddaughter, neither of whom has splenomegaly or marked dyslipidemia.
|
24314356 |
2014 |
|
Dyslipidemias
|
0.400 |
GeneticVariation
|
group |
BEFREE |
Identification and characterization of a novel apolipoprotein E variant, apolipoprotein E3' (Arg136-->His): association with mild dyslipidemia and double pre-beta very low density lipoproteins.
|
7706948 |
1995 |
|
Dyslipidemias
|
0.400 |
GeneticVariation
|
group |
BEFREE |
Apolipoprotein E gene polymorphisms are strong predictors of inflammation and dyslipidemia in rheumatoid arthritis.
|
22174202 |
2012 |
|
Dyslipidemias
|
0.400 |
GeneticVariation
|
group |
BEFREE |
We confirm that human schistosomiasis causes dyslipidemia and report for the first time that certain changes in plasma lipid and lipoprotein levels depend on APOE gene polymorphism.
|
25051269 |
2014 |
|
Dyslipidemias
|
0.400 |
GeneticVariation
|
group |
BEFREE |
None of the combined APOA5-APOE polymorphisms increased risk for dyslipidemia.
|
21132386 |
2011 |
|
Dyslipidemias
|
0.400 |
GeneticVariation
|
group |
BEFREE |
Polymorphism of the apolipoprotein E (APOE) gene has been associated with dyslipidemia and cardiovascular disease.
|
16815257 |
2006 |
|
Dyslipidemias
|
0.400 |
GeneticVariation
|
group |
BEFREE |
APOE genotypes and dyslipidemias in a sample of the Portuguese population.
|
16176168 |
2005 |
|
Dyslipidemias
|
0.400 |
GeneticVariation
|
group |
BEFREE |
Thus, apo E gene locus influences not only the levels of certain lipoprotein variables during young adulthood, but also modulates the association between obesity and dyslipidemias.
|
11398147 |
2001 |
|
Dyslipidemias
|
0.400 |
GeneticVariation
|
group |
LHGDN |
Variation in 5' promoter region of the APOE gene contributes to predicting ischemic heart disease (IHD) in the population at large: the Copenhagen City Heart Study.
|
17535270 |
2007 |
|
Dyslipidemias
|
0.400 |
GeneticVariation
|
group |
BEFREE |
The study aimed to assess whether the common APOE polymorphism is associated with lipid profiles and dyslipidemia, and it could be modulated by obesity-related traits (body mass index, waist circumference, hip circumference, and waist-to-hip ratio) in Vietnamese children.
|
27724906 |
2016 |
|
Dyslipidemias
|
0.400 |
GeneticVariation
|
group |
BEFREE |
In this population, we analyzed the relationship between background risk factors [age, gender, the G1691A polymorphisms of factor V gene, the C677T polymorphisms of the methylenetetrahydrofolate reductase (MTHFR) gene, the 844ins68bp polymorphisms of the cystathionine-beta-synthase (CBS) gene, and the apolipoprotein E (APOE) polymorphisms] and environmental risk factors, both atherogenic (smoke, hypertension, diabetes, dyslipidemia, obesity) and thrombogenic (smoke, homocysteine, fibrinogen) by a Markov block-recursive modeling approach.
|
16194201 |
2005 |
|
Dyslipidemias
|
0.400 |
GeneticVariation
|
group |
BEFREE |
Apolipoprotein E alleles are important genetic markers for dyslipidemia and CHD.
|
7966894 |
1994 |
|
Dyslipidemias
|
0.400 |
GeneticVariation
|
group |
BEFREE |
In recent studies, apolipoprotein E (apo E) genetic polymorphism in association with dyslipidemia have been proposed as the one of the risk factors for the development of diabetic nephropathy.
|
17624465 |
2007 |
|
Dyslipidemias
|
0.400 |
GeneticVariation
|
group |
BEFREE |
The role of apolipoprotein E polymorphism in improving dyslipidemia in obese adolescents following physical exercise and National Cholesterol Education Program Step II intervention.
|
25870958 |
2015 |
|
Dyslipidemias
|
0.400 |
GeneticVariation
|
group |
BEFREE |
Presence of APOE epsilon4/* seems to increase the risk for dementia and AD independently of its effect on dyslipidemia and atherogenesis.
|
10668701 |
2000 |