APOE, apolipoprotein E, 348

N. diseases: 1049; N. variants: 62
Disease: Congenital Heart Defects ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0018798
Disease: Congenital Heart Defects
Congenital Heart Defects 		0.030 GeneticVariation group BEFREE The APOE ε2 allele has been associated with worse neurodevelopmental (ND) outcome after repair of congenital heart defects (CHD) in infancy. 25282659 2014
CUI: C0018798
Disease: Congenital Heart Defects
Congenital Heart Defects 		0.030 GeneticVariation group BEFREE The goal was to evaluate polymorphisms of the APOE gene as modifiers of neurobehavioral outcomes for preschool-aged children with congenital heart defects, after cardiac surgery. 19564306 2009
CUI: C0018798
Disease: Congenital Heart Defects
Congenital Heart Defects 		0.030 GeneticVariation group BEFREE A single-institution prospective study of patients <or=6 months of age undergoing cardiopulmonary bypass for repair of congenital heart defects was undertaken to evaluate the association between apolipoprotein E genotype and postoperative neurodevelopmental dysfunction. 14688681 2003