|
HIV Infections
|
0.100 |
GeneticVariation
|
group |
BEFREE |
We used multivariable logistic regression to predict regional Aβ plaque or p-tau pathology based on demographic factors, apolipoprotein E (APOE) genotypes, HIV disease-related factors, and regional gliosis.
|
31144289 |
2019 |
|
HIV Infections
|
0.100 |
Biomarker
|
group |
BEFREE |
Aging and Apolipoprotein E in HIV Infection.
|
29987582 |
2018 |
|
HIV Infections
|
0.100 |
Biomarker
|
group |
BEFREE |
Correction to: Aging and apolipoprotein E in HIV infection.
|
30456529 |
2018 |
|
HIV Infections
|
0.100 |
Biomarker
|
group |
BEFREE |
The apolipoprotein ε4 gene allele and the apolipoprotein E4 protein (ApoE4) are important host susceptibility factors linked to neurocognitive disorders associated with HIV infection or Alzheimer's disease.
|
28321820 |
2017 |
|
HIV Infections
|
0.100 |
GeneticVariation
|
group |
BEFREE |
The association between lipid markers (total cholesterol, low-density lipoprotein cholesterol [LDL-C], high-density lipoprotein cholesterol [HDL-C], and triglycerides), APOE genotype, and cognitive decline in HIV infection was examined using mixed-effects models.
|
27448678 |
2016 |
|
HIV Infections
|
0.100 |
Biomarker
|
group |
BEFREE |
These data replicate and strengthen prior findings of the lack of association between ApoE ε4 and cognitive outcomes in HIV disease.
|
25388225 |
2015 |
|
HIV Infections
|
0.100 |
Biomarker
|
group |
BEFREE |
The combined effects of HIV infection and APOE ε4 may lead to greater cognitive deficits, especially in those with greater neuroinflammation.
|
24850492 |
2014 |
|
HIV Infections
|
0.100 |
AlteredExpression
|
group |
BEFREE |
We used the Memory Island (MI) test to study the effects of HIV infection, apolipoprotein E (ApoE) allele status, and cerebral spinal fluid (CSF) ApoE protein levels on spatial learning and memory in our cohort of Hispanic women.
|
22972599 |
2012 |
|
HIV Infections
|
0.100 |
GeneticVariation
|
group |
BEFREE |
However, APOE ε 4 allele has been associated with greater incidence of HIV-associated dementia and accelerated progression of HIV infection.
|
21184197 |
2011 |
|
HIV Infections
|
0.100 |
GeneticVariation
|
group |
BEFREE |
The apolipoprotein E (APOE) ε4 allele may accelerate the progression of HIV disease, and increase the risk for developing HIV-associated neurocognitive disorder (HAND).
|
21803164 |
2011 |
|
HIV Infections
|
0.100 |
Biomarker
|
group |
BEFREE |
This review summarises how apoE4 may be involved in the infection incidence and associated pathologies of specific infectious diseases, namely hepatitis C, human immunodeficiency virus disease and herpes simplex.ApoE4 seems to be protective against chronic hepatitis C virus infection and retards fibrosis progression.
|
20109174 |
2010 |
|
HIV Infections
|
0.100 |
Biomarker
|
group |
BEFREE |
These findings establish apoE as a determinant of HIV-AIDS pathogenesis and raise the possibility that current efforts to convert apoE4 to an "apoE3-like" molecule to treat Alzheimer's disease might also have clinical applicability in HIV disease.
|
18562290 |
2008 |
|
HIV Infections
|
0.100 |
GeneticVariation
|
group |
BEFREE |
In conclusion, opiate abusers with HIV infection and the ApoE4 allele may be at increased risk of developing dementia.
|
16697650 |
2006 |