APOE, apolipoprotein E, 348

N. diseases: 1049; N. variants: 62
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C2936351
Disease: Fibroatheroma
Fibroatheroma
0.300 Biomarker disease CTD_human Kuwanon G attenuates atherosclerosis by upregulation of LXRα-ABCA1/ABCG1 and inhibition of NFκB activity in macrophages. 29355567 2018
CUI: C2936351
Disease: Fibroatheroma
Fibroatheroma
0.300 Biomarker disease CTD_human Effects of Icariin on Atherosclerosis and Predicted Function Regulatory Network in ApoE Deficient Mice. 30533443 2018
CUI: C2936351
Disease: Fibroatheroma
Fibroatheroma
0.300 Biomarker disease CTD_human Using the Apolipoprotein E Knock-Out Mouse Model to Define Atherosclerotic Plaque Changes Induced by Low Dose Arsenic. 30376133 2018
CUI: C2936351
Disease: Fibroatheroma
Fibroatheroma
0.300 Biomarker disease CTD_human Perinatal Bisphenol A Exposure Increases Atherosclerosis in Adult Male PXR-Humanized Mice. 29425287 2018
CUI: C2936351
Disease: Fibroatheroma
Fibroatheroma
0.300 Biomarker disease CTD_human Notoginsenoside R1 attenuates atherosclerotic lesions in ApoE deficient mouse model. 24933211 2014
CUI: C2936351
Disease: Fibroatheroma
Fibroatheroma
0.300 Biomarker disease CTD_human Diesel exhaust particulate increases the size and complexity of lesions in atherosclerotic mice. 24330719 2013
CUI: C2936351
Disease: Fibroatheroma
Fibroatheroma
0.300 Biomarker disease CTD_human Copper chelation by tetrathiomolybdate inhibits vascular inflammation and atherosclerotic lesion development in apolipoprotein E-deficient mice. 22770994 2012
CUI: C2936351
Disease: Fibroatheroma
Fibroatheroma
0.300 Biomarker disease CTD_human Proatherogenic macrophage activities are targeted by the flavonoid quercetin. 22869926 2012
CUI: C2936351
Disease: Fibroatheroma
Fibroatheroma
0.300 Biomarker disease CTD_human Effects of paricalcitol and enalapril on atherosclerotic injury in mouse aortas. 20720404 2010
CUI: C2936351
Disease: Fibroatheroma
Fibroatheroma
0.300 Biomarker disease CTD_human Thieno[2,3-c]isoquinolin-5-one, a potent poly(ADP-ribose) polymerase inhibitor, promotes atherosclerotic plaque regression in high-fat diet-fed apolipoprotein E-deficient mice: effects on inflammatory markers and lipid content. 19124646 2009
CUI: C2936351
Disease: Fibroatheroma
Fibroatheroma
0.300 Biomarker disease CTD_human Poly(ADP-ribose) polymerase inhibition reduces atherosclerotic plaque size and promotes factors of plaque stability in apolipoprotein E-deficient mice: effects on macrophage recruitment, nuclear factor-kappaB nuclear translocation, and foam cell death. 17438151 2007