Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Behavioral and psychological symptoms of dementia
0.100 GeneticVariation phenotype BEFREE A multiple linear regression analysis was conducted to determine the effects of the APOE genotype on the relationships between morphometric features and neuropsychiatric symptoms in SCD. 31159873 2019
Behavioral and psychological symptoms of dementia
0.100 GeneticVariation phenotype BEFREE As few studies have examined the relationship between the apolipoprotein E (APOE) gene and clinical outcomes after military-related traumatic brain injury (TBI), we aimed to determine whether the ε4 allele of the APOE gene influences neuropsychiatric symptoms in veterans with a history of mild-to-moderate TBI. 29463164 2018
Behavioral and psychological symptoms of dementia
0.100 GeneticVariation phenotype BEFREE The results show that in Thai individuals, the presence of ApoE4 allele is accompanied by a multifarious decline in neurocognitive functions and behavioral features and that ApoE3 may convey protection against neuropsychiatric symptoms and a decline in social skills. 29307083 2018
Behavioral and psychological symptoms of dementia
0.100 GeneticVariation phenotype BEFREE It was hypothesized that neuropsychiatric symptoms and the apolipoprotein E genotype increase the likelihood of Alzheimer's disease development. 27111252 2017
Behavioral and psychological symptoms of dementia
0.100 Biomarker phenotype BEFREE Considering the role of apolipoprotein E in the life cycle of the virus, the findings shed interesting new light upon possible pathomechanisms behind the development of neuropsychiatric symptoms in hepatitis C infection. 26306786 2016
Behavioral and psychological symptoms of dementia
0.100 Biomarker phenotype BEFREE The interaction between gender and ApoE ε4 status should be considered in studies on neuropsychiatric symptoms of AD. 26538817 2015
Behavioral and psychological symptoms of dementia
0.100 GeneticVariation phenotype BEFREE The differences in neuropsychiatric symptoms between the two groups were most pronounced in patients with the APOE ε4 allele, suggesting that neuropsychiatric symptoms in AD may be influenced by the APOE genotype. 25322926 2015
Behavioral and psychological symptoms of dementia
0.100 GeneticVariation phenotype BEFREE This study analyzed the effects of the BChE and ApoE genotypes on the cortical thickness of patients with AD and examined how these genotypes affect the neuropsychiatric symptoms of AD. 24479631 2014
Behavioral and psychological symptoms of dementia
0.100 GeneticVariation phenotype BEFREE Sleep length and architecture are potential markers of progressive cognitive impairment, while neuropsychiatric symptoms and APOE4- haplotypes have been associated with more sleep complaints in patients with dementia due to Alzheimer's disease (AD). 25194823 2014
Behavioral and psychological symptoms of dementia
0.100 Biomarker phenotype BEFREE The impact of APOE status on relationship of biomarkers of vascular risk and systemic inflammation to neuropsychiatric symptoms in Alzheimer's disease. 24577461 2014
Behavioral and psychological symptoms of dementia
0.100 Biomarker phenotype BEFREE After adjusting for age and education, neuropsychiatric symptoms and APOE ε4 were independently associated with CIND and dementia status at baseline (compared with cognitively normal). 22927174 2013
Behavioral and psychological symptoms of dementia
0.100 GeneticVariation phenotype BEFREE Apolipoprotein E genotypes and neuropsychiatric symptoms and syndromes in late-onset Alzheimer's disease. 21763789 2012
Behavioral and psychological symptoms of dementia
0.100 Biomarker phenotype BEFREE This study investigates the association between APOE and neuropsychiatric symptoms in a large sample of clinically well-characterized subjects with probable AD (n=790) who were systematically evaluated using the Consortium to Establish a Registry for Alzheimer's Disease (CERAD) Behavioral Rating Scale for Dementia (BRSD). 23270420 2012
Behavioral and psychological symptoms of dementia
0.100 GeneticVariation phenotype BEFREE Apolipoprotein E polymorphism and behavioral and psychological symptoms of dementia in patients with Alzheimer disease. 21617520 2012
Behavioral and psychological symptoms of dementia
0.100 Biomarker phenotype BEFREE Apolipoprotein E (APOE) ε4 status may modify the effects of sex hormones on neuropsychiatric symptoms. 22398564 2012
Behavioral and psychological symptoms of dementia
0.100 GeneticVariation phenotype BEFREE The APOE polymorphism in Alzheimer's disease patients with neuropsychiatric symptoms and syndromes. 21905100 2011
Behavioral and psychological symptoms of dementia
0.100 GeneticVariation phenotype BEFREE Neuropsychiatric symptoms and the APOE genotype in Alzheimer's disease. 19590821 2009
Behavioral and psychological symptoms of dementia
0.100 GeneticVariation phenotype BEFREE There have been inconclusive results to date on the association between the Apolipoprotein E (ApoE) genotype and neuropsychiatric symptoms (NPS) in Alzheimer's disease (AD). 16390371 2006
Behavioral and psychological symptoms of dementia
0.100 GeneticVariation phenotype BEFREE A highly statistically significant association was seen between APOE genotypes and interferon-induced neuropsychiatric symptoms. 14709760 2004