IGF2, insulin like growth factor 2, 3481

N. diseases: 604; N. variants: 19
Disease: Adrenal Gland Pheochromocytoma ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C4551683
Disease: Adrenal Gland Pheochromocytoma
Adrenal Gland Pheochromocytoma 		0.050 Biomarker disease BEFREE Overexpression of insulin growth factor 2 (IGF2) is a hallmark of adrenocortical carcinomas and pheochromocytomas. 26400872 2015
CUI: C4551683
Disease: Adrenal Gland Pheochromocytoma
Adrenal Gland Pheochromocytoma 		0.050 AlteredExpression disease BEFREE Glucocorticoids increase insulin-like growth factor-II mRNA accumulation in cultured human phaeochromocytoma cells. 7964281 1994
CUI: C4551683
Disease: Adrenal Gland Pheochromocytoma
Adrenal Gland Pheochromocytoma 		0.050 AlteredExpression disease BEFREE The IGF-II mRNA content was high in pheochromocytomas, as reported previously. 8370710 1993
CUI: C4551683
Disease: Adrenal Gland Pheochromocytoma
Adrenal Gland Pheochromocytoma 		0.050 Biomarker disease BEFREE The constitutive expressions of c-fos and c-myc genes may be interpreted to mean that pheochromocytoma is in a state of growth stimulation in vivo by growth factors, including IGF-II. 2405002 1990
CUI: C4551683
Disease: Adrenal Gland Pheochromocytoma
Adrenal Gland Pheochromocytoma 		0.050 Biomarker disease BEFREE The high amounts of IGF-II in the pheochromocytomas were not reflected, however, by a corresponding increase of mRNA. 3029761 1987