IGF2R, insulin like growth factor 2 receptor, 3482

N. diseases: 166; N. variants: 18
Disease: Squamous cell carcinoma ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0007137
Disease: Squamous cell carcinoma
Squamous cell carcinoma 		0.040 AlteredExpression disease BEFREE It has been shown that expression of wild-type M6P/IGF2R reduces the tumorigenic and invasive properties of receptor-deficient SCC-VII squamous cell carcinoma cells. 23347038 2013
CUI: C0007137
Disease: Squamous cell carcinoma
Squamous cell carcinoma 		0.040 GeneticVariation disease LHGDN Loss of imprinting of IGF2 and H19, loss of heterozygosity of IGF2R and CTCF, and Helicobacter pylori infection in laryngeal squamous cell carcinoma. 18604514 2008
CUI: C0007137
Disease: Squamous cell carcinoma
Squamous cell carcinoma 		0.040 GeneticVariation disease BEFREE Insulin-like growth factor II receptor gene-167 genotype increases the risk of oral squamous cell carcinoma in humans. 12543777 2003
CUI: C0007137
Disease: Squamous cell carcinoma
Squamous cell carcinoma 		0.040 GeneticVariation disease BEFREE Nineteen of 22 (86%) patients were informative (heterozygous), and 11/19 (58%) squamous cell carcinomas of the lung had LOH at the M6P/IGF2R locus. 10734317 2000