Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0426980
Disease: Motor symptoms
Motor symptoms
0.030 Biomarker phenotype BEFREE Thus, alterations in body weight are present in ALS patients already decades before clinical manifestation of ALS, while weight loss precedes motor symptoms of several years and is associated with poor prognosis. 28975435 2017
CUI: C0426980
Disease: Motor symptoms
Motor symptoms
0.030 GeneticVariation phenotype BEFREE Early changes of neuromuscular transmission in the SOD1(G93A) mice model of ALS start long before motor symptoms onset. 24040091 2013
CUI: C0426980
Disease: Motor symptoms
Motor symptoms
0.030 Biomarker phenotype BEFREE The mice heterozygotic for the human mutated SOD1 (D and DF) showed distinct ALS-like motor symptoms, whereas the mice heterozygotic for the normal SOD1 (W and WF) mice did not. 15857664 2005