Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C2363741
Disease: HIV-1 infection
HIV-1 infection
0.040 Biomarker disease BEFREE We review recent studies that describe mechanisms of B-cell dysregulation in chronic HIV-1 infection associated with IgG3 and T-bet. 30973418 2019
CUI: C2363741
Disease: HIV-1 infection
HIV-1 infection
0.040 GeneticVariation disease BEFREE HIV-1-specific IgG3 antibodies have been correlated with decreased risk of HIV-1 infection in the RV144 trial, which included a CNPV-based vector (Yates et al.(Sci Transl Med, 6(228) p228, 2014). 26153454 2015
CUI: C2363741
Disease: HIV-1 infection
HIV-1 infection
0.040 Biomarker disease BEFREE Env-specific IgG and IgG3 Abs, IgG avidity, and neutralizing Abs inversely correlated with CRF01_AE 169K HIV-1 infection risk in the CT- or TT-carrying vaccine recipients only. 25105367 2014
CUI: C2363741
Disease: HIV-1 infection
HIV-1 infection
0.040 Biomarker disease BEFREE RANTES.her2.IgG3 bound specifically to the CCR5 chemokine receptor, as demonstrated by flow cytometry, and inhibited HIV-1 infection via the CCR5 coreceptor. 9759898 1998