IL2, interleukin 2, 3558

N. diseases: 950; N. variants: 5
Disease: Diabetes Mellitus ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0011849
Disease: Diabetes Mellitus
Diabetes Mellitus 		0.060 Biomarker group BEFREE Interleukin-2 receptor antagonists: Protective factors against new-onset diabetes after renal transplantation. 29577632 2018
CUI: C0011849
Disease: Diabetes Mellitus
Diabetes Mellitus 		0.060 Biomarker group BEFREE Induction of diabetes by streptozotocin was associated with reduction of body weight and insulin level, increase in glucose level and pro-inflammatory cytokines (IL-1β, IL-6, and TNF-α), and reduction in IL-2 and IL-4 levels. 28142150 2017
CUI: C0011849
Disease: Diabetes Mellitus
Diabetes Mellitus 		0.060 Biomarker group BEFREE Intramuscular vaccination of recombinant adeno-associated virus to 10-wk-old NOD female mice and a subsequent 3 wk induction of IL-2 was sufficient to prevent diabetes and block the progression of insulitis. 21317396 2011
CUI: C0011849
Disease: Diabetes Mellitus
Diabetes Mellitus 		0.060 Biomarker group BEFREE Humanized NOD/LtSz-scid IL2 receptor common gamma chain knockout mice in diabetes research. 17332083 2007
CUI: C0011849
Disease: Diabetes Mellitus
Diabetes Mellitus 		0.060 GeneticVariation group BEFREE Upregulation of Foxp3 expression in mouse and human Treg is IL-2/STAT5 dependent: implications for the NOD STAT5B mutation in diabetes pathogenesis. 17130555 2006
CUI: C0011849
Disease: Diabetes Mellitus
Diabetes Mellitus 		0.060 Biomarker group BEFREE Immune dysfunction in diabetes-prone BB rats. Interleukin 2 production and other mitogen-induced responses are suppressed by activated macrophages. 6607315 1984