IL2RA, interleukin 2 receptor subunit alpha, 3559

N. diseases: 540; N. variants: 43
Disease: Primary sclerosing cholangitis ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0566602
Disease: Primary sclerosing cholangitis
Primary sclerosing cholangitis 		0.130 GeneticVariation disease BEFREE Reduced Treg numbers in patients with PSC are associated with polymorphisms in the IL2RA gene. 24412607 2014
CUI: C0566602
Disease: Primary sclerosing cholangitis
Primary sclerosing cholangitis 		0.130 Biomarker disease BEFREE These results strongly implicate the role of IL-2/IL2RA pathway in PSC and provide further confirmation of MST1 association. 22554193 2012
CUI: C0566602
Disease: Primary sclerosing cholangitis
Primary sclerosing cholangitis 		0.130 GeneticVariation disease GWASDB Genome-wide association analysis in primary sclerosing cholangitis identifies two non-HLA susceptibility loci. 21151127 2011
CUI: C0566602
Disease: Primary sclerosing cholangitis
Primary sclerosing cholangitis 		0.130 Biomarker disease BEFREE Immunohistochemically, CD4(+)CD25(+)Foxp3(+) cells were frequently found in AIPC, while few were found in PSC and other disease controls. 17518371 2007