IL2RA, interleukin 2 receptor subunit alpha, 3559

N. diseases: 540; N. variants: 43
Disease: Childhood Leukemia ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C1332977
Disease: Childhood Leukemia
Childhood Leukemia 		0.050 Biomarker disease BEFREE Overexpression of interleukin 2 receptor (IL2R) in hematological malignancies has been utilized to target leukemia. 26984209 2016
CUI: C1332977
Disease: Childhood Leukemia
Childhood Leukemia 		0.050 Biomarker disease BEFREE SPRSV2 exhibited potent cytotoxicity effectively targeted to alpha subunit of IL2R on various leukemia cell lines. 20580754 2010
CUI: C1332977
Disease: Childhood Leukemia
Childhood Leukemia 		0.050 Biomarker disease BEFREE Moreover, in mice, intrasplenic injection of IDO+ leukemia/ lymphoma A20 cells induces the expansion of bona fide T(reg) cells by conversion of CD4+CD25- T cells; this effect is counteracted by 1-MT treatment. 17164341 2007
CUI: C1332977
Disease: Childhood Leukemia
Childhood Leukemia 		0.050 AlteredExpression disease BEFREE Interleukin 2 (IL 2) receptor (IL 2-R) is constitutively expressed on T cell lines established from the patients with adult T cell leukemia (ATL), which is a human T cell leukemia lymphoma virus (HTLV-1)(+) T4(+)-leukemia endemic in Japan, the United States, and other countries. 2999237 1985
CUI: C1332977
Disease: Childhood Leukemia
Childhood Leukemia 		0.050 AlteredExpression disease BEFREE This apparent biphenotypic status might reflect a transformation-associated expression of the Tac antigen in this leukemia. 6192435 1983