Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0948192
Disease: Primary infection NOS
Primary infection NOS
0.010 Biomarker disease BEFREE There was no upregulation of co-stimulatory molecules CD86, CD80, CD40, and reduced surface expression of HLA-DR and CD123 (IL-3R-α). pDC loss from the circulation was associated with active caspase-3, suggesting pDC apoptosis during primary infection. pDC remained responsive to TLR stimulation, producing IFN-α and upregulating HLA-DR, CD86, CD123 at peak-infection. 28572564 2017