|
Muscle damage
|
0.100 |
Biomarker
|
phenotype |
BEFREE |
The intervention group demonstrated a significant increase in serum 25-hydroxyvitamin D levels (53.93, 10.68 ng/mL, P < 0.0001), which is the best indicator of vitamin D levels in the body, with no change in the circulating markers of muscle damage and CRP (P ˃ 0.05) but showed increased IL-6 (P = 0.034).
|
30419498 |
2019 |
|
Muscle damage
|
0.100 |
Biomarker
|
phenotype |
BEFREE |
Blood samples were collected immediately before, after, 2, and 4 hours after the games to assess muscle damage (creatine kinase [CK] and alpha-actin) and hormonal responses (interleukin-6 [IL-6], cortisol, and testosterone).
|
29781940 |
2019 |
|
Muscle damage
|
0.100 |
GeneticVariation
|
phenotype |
BEFREE |
Israeli runners of Ethiopian origin had a greater frequency of the PPARD CC + PARGC1A Gly/Gly polymorphism, associated with improved endurance performance, compared with Israeli runners of non-Ethiopian origins (24 vs. 3%, respectively, p < 0.01); a lower frequency of the ACSL AA polymorphism, favoring endurance trainability (8 vs. 20%, respectively, p < 0.05); a greater frequency of the ACTN3 RR polymorphism, associated with sprint performance (35 vs. 20%, respectively, p < 0.05); a greater frequency of the MCT1 AA genotype, associated with improved lactate transport (65 vs. 45%, respectively, p < 0.05); and a lower frequency of IL-6 174C carriers, associated with reduced postexercise muscle damage (27 vs. 40%, respectively, p < 0.01).
|
30741858 |
2019 |
|
Muscle damage
|
0.100 |
Biomarker
|
phenotype |
BEFREE |
In order to verify the effects of the supplementation protocol markers of muscle damage as lactate dehydrogenase (LDH) and creatine kinase (CK), and inflammatory markers tumor necrosis factor-α (TNF-α) and interleukin-6 (IL-6) were quantified, also triathletes' performance was evaluated by exhaust test on a treadmill.
|
28745470 |
2018 |
|
Muscle damage
|
0.100 |
Biomarker
|
phenotype |
BEFREE |
Muscle strength (MVC), muscle damage (CK), oxidative stress (GPx), inflammation (IL6) and volunteer-reported muscle soreness intensity were assessed pre and post exercise.
|
29410606 |
2018 |
|
Muscle damage
|
0.100 |
Biomarker
|
phenotype |
BEFREE |
In terms of muscle damage and inflammatory markers, we observed an overall moderate decrease in creatine kinase [SMD (95% CI) = -0.37 (-0.58 to -0.16), I<sup>2</sup> = 40.15%] and overall small decreases in interleukin-6 [SMD (95% CI) = -0.36 (-0.60 to -0.12), I<sup>2</sup> = 0%] and C-reactive protein [SMD (95% CI) = -0.38 (-0.59 to-0.14), I<sup>2</sup> = 39%].
|
29755363 |
2018 |
|
Muscle damage
|
0.100 |
Biomarker
|
phenotype |
BEFREE |
Along with enhanced FAO capacity during exhaustive exercise, a KD may also alter IL-6 synthesis and secretion profile, thus contribute to fatty acid mobilization, ketolysis, lipolysis and preventing muscle damage.
|
30405021 |
2018 |
|
Muscle damage
|
0.100 |
Biomarker
|
phenotype |
BEFREE |
Markers of muscle damage (LDH, CK, and Mb) were significantly elevated following both HV and HI (p < 0.05), while cortisol and IL-6 concentrations were significantly elevated at P-30 min following HV only (p < 0.001 and p < 0.05, respectively).
|
28447186 |
2017 |
|
Muscle damage
|
0.100 |
GeneticVariation
|
phenotype |
BEFREE |
If tissue damage occurs, immune cells infiltrate and secrete cytokines, including IL-6, to repair skeletal muscle damage.
|
28507168 |
2017 |
|
Muscle damage
|
0.100 |
Biomarker
|
phenotype |
BEFREE |
The main aim of this study was to assess and compare the kinetics of blood brain-derived neurotrophic factor (BDNF), norepinephrine (NE) and cortisol (as stress indicators) and proinflammatory (IL-6) and anti-inflammatory (IL-10) cytokines within 24 hours after metabolically demanding SIE and after muscle damage inducing SSE.
|
28456776 |
2017 |
|
Muscle damage
|
0.100 |
GeneticVariation
|
phenotype |
BEFREE |
We present an adolescent elite water polo player who despite a genetic predisposition to develop exercise-induced severe muscle damage due to carrying the IL-6 174C allele single-nucleotide polymorphism, developed acute rhabdomyolysis only after a vigorous out-of-water training, suggesting that water polo training may be more suitable for genetically predisposed athletes.
|
25970495 |
2015 |
|
Muscle damage
|
0.100 |
GeneticVariation
|
phenotype |
BEFREE |
Interleukin-6 -174G/C gene polymorphism affects muscle damage response to acute eccentric resistance exercise in elderly obese women.
|
23981903 |
2013 |
|
Muscle damage
|
0.100 |
Biomarker
|
phenotype |
BEFREE |
Blood samples were taken from athletes pre-eccentric training, immediately after (post), 2- and 4-h post-eccentric training to determine hormone responses (cortisol and testosterone), muscle damage (CK and α-actin), and inflammatory responses (IL-6).
|
21842214 |
2012 |
|
Muscle damage
|
0.100 |
AlteredExpression
|
phenotype |
BEFREE |
We evaluated changes in markers of exercise-induced skeletal muscle damage and inflammation [serum creatine kinase (CK), serum lactate dehydrogenase (LDH), and skeletal muscle mRNA expression of IL-6, IL-8, IL-15, and TNF-alpha] in postmenopausal women after a high-intensity resistance exercise bout.
|
19574506 |
2009 |