AQP2, aquaporin 2, 359

N. diseases: 114; N. variants: 41
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0018802
Disease: Congestive heart failure
Congestive heart failure
0.040 Biomarker disease BEFREE Immunofluorescence studies of kidney sections confirmed the reduced signaling of ENaC and AQP2 in the CHF+RDN rats compared with the CHF rats. 31490733 2019
CUI: C0018802
Disease: Congestive heart failure
Congestive heart failure
0.040 Biomarker disease BEFREE Expression and subcellular distribution of aquaporin 2 (AQP2) were detected by immunoblotting and immunofluorescence in mouse inner medullary collecting duct-3 (mIMCD-3) cells and congestive heart failure model rats. 30797506 2019
CUI: C0018802
Disease: Congestive heart failure
Congestive heart failure
0.040 AlteredExpression disease BEFREE Expression of AQP2 was evaluated by immunoblotting, immunohistochemical staining, and quantitative real-time PCR (qPCR) in CHF rat model and mouse inner medullary collecting duct (mIMCD) 3 cell line. 31153818 2019
CUI: C0018802
Disease: Congestive heart failure
Congestive heart failure
0.040 Biomarker disease BEFREE Dysregulation of AQP2 is also a common cause of water retention and hyponatremia that exacerbate the prognosis of congestive heart failure and hepatic cirrhosis. 24129558 2014