IL13, interleukin 13, 3596

N. diseases: 587; N. variants: 9
Disease: IgE-mediated food allergy ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C4554344
Disease: IgE-mediated food allergy
IgE-mediated food allergy 		0.050 Biomarker disease BEFREE We found FLG, HLA, IL10, IL13, as well as some evidence for other variants (SPINK5, SERPINB and C11orf30) that are associated with food allergy. 30835860 2019
CUI: C4554344
Disease: IgE-mediated food allergy
IgE-mediated food allergy 		0.050 GeneticVariation disease BEFREE We investigate the food allergy candidate locus Interleukin13 (IL13) as an example. 29985321 2018
CUI: C4554344
Disease: IgE-mediated food allergy
IgE-mediated food allergy 		0.050 Biomarker disease BEFREE IgE-mediated FA was induced in BALB/c mice by oral gavage with medium-chain triglycerides (MCTs) plus egg white (EW) and was characterized by increased numbers of lamina propria T<sub>H</sub>2 cells, mast cells, and eosinophils, shock (hypothermia), mast cell degranulation (increased serum mouse mast cell protease 1), increased serum IgG<sub>1</sub> anti-EW and IgE levels, and increased IL-4 and IL-13 secretion after MCT/EW challenge. 28552763 2018
CUI: C4554344
Disease: IgE-mediated food allergy
IgE-mediated food allergy 		0.050 GeneticVariation disease BEFREE Here, we sought to investigate whether genetic polymorphisms at IL13 are associated with the development of challenge-proven IgE-mediated food allergy. 28544327 2017
CUI: C4554344
Disease: IgE-mediated food allergy
IgE-mediated food allergy 		0.050 Biomarker disease BEFREE Parental-reported food allergy was reported less often when IL13 was detectable in colostrum OR 0.10 (95% CI 0.01-0.83). 28538696 2017