IL17A, interleukin 17A, 3605

N. diseases: 1074; N. variants: 19
Disease: AGEP ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0863129
Disease: AGEP
AGEP 		0.020 Biomarker disease BEFREE The physiopathology of AGEP remains unclear, but an involvement of innate and acquired immune cells together with resident cells (keratinocytes), which recruit and activate neutrophils via production of cytokines/chemokines such as IL-17, IL-36, granulocyte-macrophage colony-stimulating factor (GM-CSF), tumor necrosis factor alpha (TNFα) and chemokine (C-X-C motif) ligand 8 (CXCL8)/IL-8, has been postulated. 27472323 2016
CUI: C0863129
Disease: AGEP
AGEP 		0.020 AlteredExpression disease BEFREE Here we show that IL-17A/F is highly expressed by innate immune cells such as neutrophils and mast cells in both AGEP and GPP. 25030504 2014