IL17A, interleukin 17A, 3605

N. diseases: 1074; N. variants: 19
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C2363774
Disease: Neutrophilic asthma
Neutrophilic asthma
0.040 AlteredExpression disease BEFREE Elevated serum IgE, oral corticosteroid dependence and IL-17/22 expression in highly neutrophilic asthma. 31439682 2019
CUI: C2363774
Disease: Neutrophilic asthma
Neutrophilic asthma
0.040 AlteredExpression disease BEFREE LTZ could alleviate the airway inflflammation in the NA mice model through increasing the IL-10 level and decreasing the IL-17 level. 29086220 2018
CUI: C2363774
Disease: Neutrophilic asthma
Neutrophilic asthma
0.040 AlteredExpression disease BEFREE As IL-17 is overexpressed in neutrophilic asthma and contributes to steroid insensitivity in different cell types, we hypothesized that NETs formation in asthmatic airways would be resistant to GC through an IL-17 mediated pathway. 29233147 2017
CUI: C2363774
Disease: Neutrophilic asthma
Neutrophilic asthma
0.040 Biomarker disease BEFREE Together, these findings reveal a TRIF-CD40-Th17 axis in the development of IL-17-associated neutrophilic asthma. 24985082 2015