|
Familial Testotoxicosis
|
0.300 |
Biomarker
|
disease |
CTD_human |
Activating mutations in the luteinizing hormone receptor gene: a human model of non-follicle-stimulating hormone-dependent inhibin production and germ cell maturation.
|
16684832 |
2006 |
|
Brain Death
|
0.200 |
Biomarker
|
phenotype |
RGD |
Gene expression profile in rat renal isografts from brain dead donors.
|
15808645 |
2005 |
|
Congenital Hypothyroidism
|
0.200 |
Biomarker
|
disease |
RGD |
Developmental expression of testis messenger ribonucleic acids in the rat following propylthiouracil-induced neonatal hypothyroidism.
|
7819453 |
1994 |
|
Endemic Cretinism
|
0.200 |
Biomarker
|
disease |
RGD |
Developmental expression of testis messenger ribonucleic acids in the rat following propylthiouracil-induced neonatal hypothyroidism.
|
7819453 |
1994 |
|
Colorectal Carcinoma
|
0.030 |
Biomarker
|
disease |
BEFREE |
THBS2, INHBB and BGN are prognostic markers and potential therapeutic targets for CRC.
|
28424419 |
2017 |
|
Colorectal Carcinoma
|
0.030 |
PosttranslationalModification
|
disease |
BEFREE |
The aim of the present study was to examine the presence of DNA sequences of five human DNA viruses (assessed by PCR): JC polyoma virus (JCV), human adenovirus (AdV), Epstein-Barr virus (EBV), Kaposi sarcoma-associated herpesvirus (KSHV/HHV8) and human papillomavirus (HPV) in a cohort of 186 sporadic colorectal cancers (CRCs) and related these data with the methylation status of six CpG island methylator phenotype (CIMP)-specific genes (MLH1, CACNA1G, NEUROG1, IGF2, SOCS1, RUNX3) and seven cancer-related genes markers (p16, MINT1, MINT2, MINT31, EN1, SCTR and INHBB) assessed by methylation-specific PCR in 186 and 134 CRC cases, respectively.
|
21625944 |
2011 |
|
Colorectal Carcinoma
|
0.030 |
Biomarker
|
disease |
BEFREE |
Given that the number of hypermethylated loci at 2q14.2 likely affects the range of silenced flanking genes, high frequency of simultaneous hypermethylation of three CpG islands (EN1, SCTR, and INHBB) may have potential influence on specific characteristics of CIMP+ colorectal cancers.
|
18403637 |
2008 |
|
Carcinoma
|
0.020 |
Biomarker
|
group |
BEFREE |
Inhibin-βA might be important during progression of CIN, whereas the inhibin-βB subunit could exert a substantial function during differentiation of cervical carcinomas.
|
21475087 |
2010 |
|
Carcinoma
|
0.020 |
Biomarker
|
group |
BEFREE |
Hypermethylation of at least one of the CpG islands analysed (EN1, SCTR, INHBB) occurred in most carcinomas (90%), with EN1 methylated in 73 and 40% of carcinomas and adenomas, respectively.
|
19384295 |
2009 |
|
Split-Hand/Foot Malformation
|
0.020 |
GeneticVariation
|
disease |
BEFREE |
The breakpoint between INHBB and GLI2 coincides with a previously identified translocation breakpoint associated with ectrodactyly.
|
19223936 |
2009 |
|
Polycystic Ovary Syndrome
|
0.020 |
Biomarker
|
disease |
LHGDN |
High serum concentration of total inhibin in polycystic ovary syndrome.
|
18423626 |
2008 |
|
Split-Hand/Foot Malformation
|
0.020 |
GeneticVariation
|
disease |
BEFREE |
To investigate whether mutation of a gene in proximity to the chromosome 2 breakpoint underlies the SHFLD, we sought independent evidence of mutations in GLI2, INHBB and two other genes (RALB and FLJ14816) in 44 unrelated patients with SHFM, SHFLD or isolated long bone deficiency.
|
17569090 |
2007 |
|
Polycystic Ovary Syndrome
|
0.020 |
Biomarker
|
disease |
LHGDN |
Luteal-phase inhibin A and follicular-phase inhibin B levels are not characteristic of patients with an elevated LH-to-FSH ratio.
|
16758344 |
2006 |
|
Malignant neoplasm of breast
|
0.010 |
GeneticVariation
|
disease |
BEFREE |
INHBB is an established locus for ER-negative breast cancer, and HABP2 and LINC01483 represent putative new breast cancer susceptibility loci, because both loci were associated with breast cancer in available meta-analysis data including 122,977 breast cancer cases and 105,974 control subjects (P < 0.05). h<sup>2</sup><sub>SNP</sub> (SE) estimates for percent dense, absolute dense, and nondense volume were 0.29 (0.07), 0.31 (0.07), and 0.25 (0.07), respectively.
|
29665850 |
2018 |
|
Breast Carcinoma
|
0.010 |
GeneticVariation
|
disease |
BEFREE |
INHBB is an established locus for ER-negative breast cancer, and HABP2 and LINC01483 represent putative new breast cancer susceptibility loci, because both loci were associated with breast cancer in available meta-analysis data including 122,977 breast cancer cases and 105,974 control subjects (P < 0.05). h<sup>2</sup><sub>SNP</sub> (SE) estimates for percent dense, absolute dense, and nondense volume were 0.29 (0.07), 0.31 (0.07), and 0.25 (0.07), respectively.
|
29665850 |
2018 |
|
estrogen receptor-negative breast cancer
|
0.010 |
GeneticVariation
|
disease |
BEFREE |
INHBB is an established locus for ER-negative breast cancer, and HABP2 and LINC01483 represent putative new breast cancer susceptibility loci, because both loci were associated with breast cancer in available meta-analysis data including 122,977 breast cancer cases and 105,974 control subjects (P < 0.05). h<sup>2</sup><sub>SNP</sub> (SE) estimates for percent dense, absolute dense, and nondense volume were 0.29 (0.07), 0.31 (0.07), and 0.25 (0.07), respectively.
|
29665850 |
2018 |
|
Secondary malignant neoplasm of lymph node
|
0.010 |
Biomarker
|
disease |
BEFREE |
Several upregulated miR-34 targets displayed elevated expression in primary human colorectal cancers that was associated with lymph-node metastases (<i>INHBB, AXL, FGFR1,</i> and <i>PDFGRB</i>) and upregulation of <i>INHBB</i> and <i>AXL</i> in primary colorectal cancer was associated with poor patient survival.
|
28363996 |
2017 |
|
Endometrial Carcinoma
|
0.010 |
AlteredExpression
|
disease |
BEFREE |
Histopathological studies suggest that elevated expression of activin/inhibin βB subunit is associated with reduced survival in non-endometrioid endometrial cancers (type II, mostly serous).
|
26384307 |
2015 |
|
Kaposi Sarcoma
|
0.010 |
GeneticVariation
|
disease |
BEFREE |
The aim of the present study was to examine the presence of DNA sequences of five human DNA viruses (assessed by PCR): JC polyoma virus (JCV), human adenovirus (AdV), Epstein-Barr virus (EBV), Kaposi sarcoma-associated herpesvirus (KSHV/HHV8) and human papillomavirus (HPV) in a cohort of 186 sporadic colorectal cancers (CRCs) and related these data with the methylation status of six CpG island methylator phenotype (CIMP)-specific genes (MLH1, CACNA1G, NEUROG1, IGF2, SOCS1, RUNX3) and seven cancer-related genes markers (p16, MINT1, MINT2, MINT31, EN1, SCTR and INHBB) assessed by methylation-specific PCR in 186 and 134 CRC cases, respectively.
|
21625944 |
2011 |
|
Adenoma
|
0.010 |
PosttranslationalModification
|
group |
BEFREE |
Hypermethylation of at least one of the CpG islands analysed (EN1, SCTR, INHBB) occurred in most carcinomas (90%), with EN1 methylated in 73 and 40% of carcinomas and adenomas, respectively.
|
19384295 |
2009 |
|
Ectrodactyly
|
0.010 |
GeneticVariation
|
disease |
BEFREE |
The breakpoint between INHBB and GLI2 coincides with a previously identified translocation breakpoint associated with ectrodactyly.
|
19223936 |
2009 |
|
Split hand foot deformity 1
|
0.010 |
GeneticVariation
|
disease |
BEFREE |
The breakpoint between INHBB and GLI2 coincides with a previously identified translocation breakpoint associated with ectrodactyly.
|
19223936 |
2009 |
|
Mammary Neoplasms
|
0.010 |
AlteredExpression
|
group |
LHGDN |
Activin and estrogen crosstalk regulates transcription in human breast cancer cells.
|
17914098 |
2007 |
|
Hypogonadism
|
0.010 |
Biomarker
|
disease |
LHGDN |
Relationship of estradiol and inhibin to the follicle-stimulating hormone variability in hypergonadotropic hypogonadism or premature ovarian failure.
|
15562017 |
2005 |
|
Ovarian Failure, Premature
|
0.010 |
Biomarker
|
disease |
LHGDN |
Relationship of estradiol and inhibin to the follicle-stimulating hormone variability in hypergonadotropic hypogonadism or premature ovarian failure.
|
15562017 |
2005 |