INSR, insulin receptor, 3643

N. diseases: 452; N. variants: 109
Disease: Brain Neoplasms ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0006118
Disease: Brain Neoplasms
Brain Neoplasms 		0.020 Biomarker group BEFREE Here, we targeted the IGF pathway using ceritinib, an off-target inhibitor of the IGF1 receptor (IGF1R) and insulin receptor (INSR), in a pediatric patient with an unclassified brain tumor and a <i>notch receptor 1</i> (<i>NOTCH1</i>) germline mutation. 31480400 2019
CUI: C0006118
Disease: Brain Neoplasms
Brain Neoplasms 		0.020 Biomarker group BEFREE The pegylated immunoliposome was targeted to brain cancer with 2 receptor-specific monoclonal antibodies (MAb), the murine 83-14 MAb to the human insulin receptor and the rat 8D3 MAb to the mouse transferrin receptor. 15173073 2004