INSR, insulin receptor, 3643

N. diseases: 452; N. variants: 109
Disease: Stomach Carcinoma ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0699791
Disease: Stomach Carcinoma
Stomach Carcinoma 		0.030 AlteredExpression disease BEFREE We investigated if (1) GCs express the IR in cancer cells (CC-IR) and vasculature (VIR), (2) IR expression is clinically relevant and may be a novel target of GC treatment. 30989432 2019
CUI: C0699791
Disease: Stomach Carcinoma
Stomach Carcinoma 		0.030 Biomarker disease BEFREE This study identifies INSR, FBXO24 and DOT1L as new candidate diffuse gastric cancer susceptibility genes, which should be validated in other populations. 25576241 2015
CUI: C0699791
Disease: Stomach Carcinoma
Stomach Carcinoma 		0.030 AlteredExpression disease BEFREE MET, HER3, IGF1R, and INSR pathways activation represent novel mechanism underlying lapatinib unresponsiveness in HER2+ gastric cancer. 24973425 2014