Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C1956346
Disease: Coronary Artery Disease
Coronary Artery Disease
0.330 GeneticVariation disease BEFREE Logistic regression analyses revealed that IRAK1 rs3027898 C/A and RANKL rs7984870 C/G polymorphisms were not associated with risk of CAD. 28115805 2017
CUI: C1956346
Disease: Coronary Artery Disease
Coronary Artery Disease
0.330 AlteredExpression disease BEFREE Significantly lower levels of IRAK-1 (0.38 ± 0.02; p = 0.0072) and TRAF-6 (0.44 ± 0.02; p = 0.0146) was found in CAD patients with the CC genotype. 23794009 2014
CUI: C1956346
Disease: Coronary Artery Disease
Coronary Artery Disease
0.330 Biomarker disease CTD_human Levels of miR-146a/b, IRAK1 mRNA, TRAF6 mRNA and TLR4 mRNA/TLR4 protein were significantly higher in the CAD group than in the non-CAD group (all P<0.01). 20524934 2010
CUI: C1956346
Disease: Coronary Artery Disease
Coronary Artery Disease
0.330 Biomarker disease BEFREE The TLR4 (Toll-like receptor 4) signal plays an important role in immunity in CAD (coronary artery disease). miR-146a/b (where miR is microRNA) regulates the TLR4 downstream molecules IRAK1 (interleukin-1-receptor-associated kinase 1) and TRAF6 (tumour-necrosis-factor-receptor-associated factor 6). 20524934 2010