IRF1, interferon regulatory factor 1, 3659

N. diseases: 257; N. variants: 7
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0007570
Disease: Celiac Disease
Celiac Disease
0.030 Biomarker disease BEFREE Dual activation of IRF1 and IRF1-regulated genes, both directly and via the interleukin-18 dependent inflammasome would drastically enhance the inflammatory response and lead to the pathological situation seen in active celiac disease. 28934294 2017
CUI: C0007570
Disease: Celiac Disease
Celiac Disease
0.030 Biomarker disease LHGDN Furthermore, untreated CD samples exhibited stronger nuclear accumulation and DNA-binding activity of IRF-1 than controls. 12788988 2003
CUI: C0007570
Disease: Celiac Disease
Celiac Disease
0.030 AlteredExpression disease BEFREE Furthermore, untreated CD samples exhibited stronger nuclear accumulation and DNA-binding activity of IRF-1 than controls. 12788988 2003
CUI: C0007570
Disease: Celiac Disease
Celiac Disease
0.030 GeneticVariation disease BEFREE IL12B and IRF1 gene polymorphisms and susceptibility to celiac disease. 14675396 2003
CUI: C0007570
Disease: Celiac Disease
Celiac Disease
0.030 GeneticVariation disease LHGDN IL12B and IRF1 gene polymorphisms and susceptibility to celiac disease. 14675396 2003