IRF2, interferon regulatory factor 2, 3660

N. diseases: 86; N. variants: 9
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0009402
Disease: Colorectal Carcinoma
Colorectal Carcinoma
0.030 Biomarker disease BEFREE The KRAS<sup>∗</sup>-IRF2-CXCL3-CXCR2 axis provides a framework for patient selection and combination therapies to enhance the effectiveness of ICB therapy in CRC. 30905761 2019
CUI: C0009402
Disease: Colorectal Carcinoma
Colorectal Carcinoma
0.030 AlteredExpression disease BEFREE Exosomal IRF-2 was highly expressed in serum exosomes isolated from CRC patients with LN metastasis relative to patients without LN metastasis and healthy controls. 30734278 2019
CUI: C0009402
Disease: Colorectal Carcinoma
Colorectal Carcinoma
0.030 Biomarker disease BEFREE Our study primarily suggests IRF-2 as a potential prognostic biomarker in CRC. 28465494 2017