IRS1, insulin receptor substrate 1, 3667

N. diseases: 233; N. variants: 15
Disease: Carcinoma ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0007097
Disease: Carcinoma
Carcinoma 		0.030 GeneticVariation group BEFREE Epidemiological studies investigating the association between the insulin receptor substrate 1 (IRS1) gene rs1801278" genes_norm="3667">Gly972Arg (rs1801278) polymorphism and various carcinomas risk reported conflicting results. 23708959 2013
CUI: C0007097
Disease: Carcinoma
Carcinoma 		0.030 Biomarker group BEFREE hsa-miR-96 up-regulates MAP4K1 and IRS1 and may function as a promising diagnostic marker in human bladder urothelial carcinomas. 21993544 2012
CUI: C0007097
Disease: Carcinoma
Carcinoma 		0.030 AlteredExpression group BEFREE IRS-1 and IGF-IR were expressed at high levels in control tissues and in well and moderately differentiated carcinomas but at low levels in poorly differentiated breast cancers. 11102895 2000