IRS1, insulin receptor substrate 1, 3667

N. diseases: 233; N. variants: 15
Disease: Diabetes Mellitus, Insulin-Dependent ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0011854
Disease: Diabetes Mellitus, Insulin-Dependent
Diabetes Mellitus, Insulin-Dependent 		0.040 Biomarker disease BEFREE In conclusion, the earlier suggested associations of IRS1 and PAX4 to T1D were not supported, suggesting that they may have been false positive results. 19956100 2009
CUI: C0011854
Disease: Diabetes Mellitus, Insulin-Dependent
Diabetes Mellitus, Insulin-Dependent 		0.040 GeneticVariation disease BEFREE A functional variant of IRS1 is associated with type 1 diabetes in families from the US and UK. 15059616 2004
CUI: C0011854
Disease: Diabetes Mellitus, Insulin-Dependent
Diabetes Mellitus, Insulin-Dependent 		0.040 GeneticVariation disease BEFREE We were unable to confirm a recently published association of the IRS1 Gly972Arg variant with type 1 diabetes. 14988278 2004
CUI: C0011854
Disease: Diabetes Mellitus, Insulin-Dependent
Diabetes Mellitus, Insulin-Dependent 		0.040 Biomarker disease BEFREE Our findings suggest a role for Arg(972) IRS-1 in conferring risk for the development of type 1 diabetes. 12606535 2003