IRS1, insulin receptor substrate 1, 3667

N. diseases: 199; N. variants: 12
Disease: Adult Acute Lymphocytic Leukemia ×
Source: BEFREE ×
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0751606
Disease: Adult Acute Lymphocytic Leukemia
Adult Acute Lymphocytic Leukemia 		0.020 Biomarker disease BEFREE NT157 has a stronger effect on ALL cells, and thus the direct inhibition of IRS1 may be a potential therapeutic target in ALL. 31042587 2019
CUI: C0751606
Disease: Adult Acute Lymphocytic Leukemia
Adult Acute Lymphocytic Leukemia 		0.020 Biomarker disease BEFREE We herein investigated the IRS1/β-catenin axis in acute lymphoblastic leukemia (ALL) cells. 27987331 2017