AR, androgen receptor, 367

N. diseases: 854; N. variants: 163
Disease: Malignant neoplasm of stomach ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0024623
Disease: Malignant neoplasm of stomach
Malignant neoplasm of stomach 		0.070 AlteredExpression disease BEFREE Upregulation of AR-v12 in primary GC tissues was significantly associated with metastasis. 30737779 2019
CUI: C0024623
Disease: Malignant neoplasm of stomach
Malignant neoplasm of stomach 		0.070 Biomarker disease BEFREE By targeting AR and EGFR using a potent AR inhibitor such as Enzalutamide, we postulate the possible crosstalk between EGFR and AR pathways in GC. 31566139 2019
CUI: C0024623
Disease: Malignant neoplasm of stomach
Malignant neoplasm of stomach 		0.070 Biomarker disease BEFREE In contrast, AR knockdown had the opposite effects on GC cell lines. 31413736 2019
CUI: C0024623
Disease: Malignant neoplasm of stomach
Malignant neoplasm of stomach 		0.070 Biomarker disease BEFREE Here, we investigated the role of AR in GC cell migration, invasion and metastatic potential. 25301736 2014
CUI: C0024623
Disease: Malignant neoplasm of stomach
Malignant neoplasm of stomach 		0.070 AlteredExpression disease BEFREE Moreover, previous data indicated that AR expression is an independent unfavorable prognostic factor in gastric cancer, suggesting that AR may play an important role in gastric carcinogenesis. 23414681 2013
CUI: C0024623
Disease: Malignant neoplasm of stomach
Malignant neoplasm of stomach 		0.070 Biomarker disease BEFREE However, ERα and AR were not independent prognostic factors for gastric cancer when multivariate survival analysis was performed. 23199240 2012
CUI: C0024623
Disease: Malignant neoplasm of stomach
Malignant neoplasm of stomach 		0.070 AlteredExpression disease BEFREE We examined AIS status in digestive tract cancers and found that all eight esophageal cancer cell lines (100%) showed AIS/TA-AIS gene overexpression, whereas 1 of 12 (8%) gastric cancer and 0 of 14 (0%) colon cancer cell lines showed AIS/TA-AIS gene expression. 11297235 2001