|
ovarian neoplasm
|
0.100 |
Biomarker
|
disease |
BEFREE |
The Role of Androgen Receptor Signaling in Ovarian Cancer.
|
30791431 |
2019 |
|
ovarian neoplasm
|
0.100 |
AlteredExpression
|
disease |
BEFREE |
Similar results have been obtained in prostate (regulation of enzymes involved in androgen synthesis and modulation of androgen receptor levels and activity) and ovary cancer.
|
30386380 |
2018 |
|
ovarian neoplasm
|
0.100 |
AlteredExpression
|
disease |
BEFREE |
Both AR and Nanog expression were obviously high in ovarian tumors.
|
29716628 |
2018 |
|
ovarian neoplasm
|
0.100 |
Biomarker
|
disease |
BEFREE |
The role of the androgen receptor in ovarian cancer carcinogenesis and its clinical implications.
|
27741511 |
2017 |
|
ovarian neoplasm
|
0.100 |
Biomarker
|
disease |
BEFREE |
Previous studies regarding the association between AR CAG repeat length and ovarian cancer risk reported inconsistent results.
|
28250337 |
2017 |
|
ovarian neoplasm
|
0.100 |
AlteredExpression
|
disease |
BEFREE |
Anti-androgen use early in the course of ovarian cancer is more likely to be effective as these data suggest that androgen receptor expression decreases with exposure to chemotherapy and this may explain the low response rates seen in clinical trials of patients heavily pre-treated with multiple courses of chemotherapy.
|
22001143 |
2012 |
|
ovarian neoplasm
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
We hypothesized that AR CAG allele length is a modifier of clinical outcome in BRCA1/2 mutation positive women with ovarian cancer.
|
19818997 |
2010 |
|
ovarian neoplasm
|
0.100 |
AlteredExpression
|
disease |
BEFREE |
The expression of Rab25 correlated positively with AR expression supporting its role as an androgen responsive gene in ovarian cancer.
|
19623182 |
2009 |
|
ovarian neoplasm
|
0.100 |
Biomarker
|
disease |
LHGDN |
We hypothesize short AR allelotypes promote aggressive ovarian cancer phenotype through modulation of epidermal growth factor receptor (EGFR) signaling.
|
18374401 |
2008 |
|
ovarian neoplasm
|
0.100 |
Biomarker
|
disease |
LHGDN |
We analyzed CAG and GGC repeat length polymorphisms in the AR gene using data from a population-based case-control study of ovarian cancer that included 594 cases and 681 controls.
|
17372242 |
2007 |
|
ovarian neoplasm
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
Previous studies of ovarian cancer and AR repeat polymorphisms have been inconsistent.
|
17372242 |
2007 |
|
ovarian neoplasm
|
0.100 |
GeneticVariation
|
disease |
LHGDN |
Androgen receptor gene methylation and exon one CAG repeat length in ovarian cancer: differences from breast cancer.
|
15545219 |
2004 |
|
ovarian neoplasm
|
0.100 |
PosttranslationalModification
|
disease |
BEFREE |
Androgen receptor gene methylation and exon one CAG repeat length in ovarian cancer: differences from breast cancer.
|
15545219 |
2004 |
|
ovarian neoplasm
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
There is no conclusive evidence of association between AR CAG repeat size and breast or ovarian cancer risk in Jewish BRCA1/2 mutation carriers.
|
12404104 |
2002 |
|
ovarian neoplasm
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
Polymorphic CAG repeat length within the androgen receptor gene: identification of a subgroup of patients with increased risk of ovarian cancer.
|
11956643 |
2002 |
|
ovarian neoplasm
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
These data suggest that AR allele length affects age of diagnosis of ovarian cancer, irrespective of BRCA mutation status.
|
11221880 |
2001 |
|
ovarian neoplasm
|
0.100 |
AlteredExpression
|
disease |
LHGDN |
The androgen receptor and DXS15-134 markers show a high rate of discordance for germline X chromosome inactivation.
|
11474658 |
2001 |
|
ovarian neoplasm
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
More recently, AR allele length was also inversely correlated with the histological grade of breast cancer, but no association was found between the AR-CAG polymorphism and the risk of either breast or ovary cancer.
|
11368874 |
2001 |
|
ovarian neoplasm
|
0.100 |
AlteredExpression
|
disease |
BEFREE |
Androgen receptor (AR) mRNA expression in HEY cells was compared to other ovarian cancer cell lines.
|
10706107 |
2000 |
|
ovarian neoplasm
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
Androgen receptor exon 1 CAG repeat length and risk of ovarian cancer.
|
10925355 |
2000 |
|
ovarian neoplasm
|
0.100 |
PosttranslationalModification
|
disease |
BEFREE |
Patterns of X-chromosome inactivation were determined by means of polymerase chain reaction amplification of the CAG-nucleotide repeat of the androgen receptor (AR) gene after methylation-sensitive restriction endonuclease digestion of blood mononuclear cell DNA from patients with invasive (n = 213) or borderline (n = 44) ovarian cancer and control subjects without a personal or family history of cancer (n = 50).
|
10050867 |
1999 |