ITGAE, integrin subunit alpha E, 3682

N. diseases: 95; N. variants: 2
Disease: Lung Neoplasms ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0024121
Disease: Lung Neoplasms
Lung Neoplasms 		0.020 Biomarker group BEFREE TGFβ Signaling Intersects with CD103 Integrin Signaling to Promote T-Lymphocyte Accumulation and Antitumor Activity in the Lung Tumor Microenvironment. 26921343 2016
CUI: C0024121
Disease: Lung Neoplasms
Lung Neoplasms 		0.020 Biomarker group BEFREE Using a human CTL system model based on a CD8(+)/CD103(-) T cell clone specific of a lung tumor-associated Ag, we demonstrated that the transcription factors Smad2/3 and NFAT-1 are two critical regulators of this process. 24477908 2014