ITGAM, integrin subunit alpha M, 3684

N. diseases: 343; N. variants: 14
Disease: Immunosuppression ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C4048329
Disease: Immunosuppression
Immunosuppression 		0.020 Biomarker disease BEFREE Thus, CXCR2(+)CD11b(+)Ly6G(hi) MDSCs mediate local immunosuppression, which limits the efficacy of checkpoint blockade in murine RMS. 24848257 2014
CUI: C4048329
Disease: Immunosuppression
Immunosuppression 		0.020 Biomarker disease BEFREE For the suppressive effect of the cells on CD8+ T lymphocytes, these findings suggest the important role of the CD11b+/CD14⁻/CD15+/CD33+ MDSCs in mediating immunosuppression in NSCLC. 19572148 2010