ITGAV, integrin subunit alpha V, 3685

N. diseases: 141; N. variants: 12
Disease: Carcinoma ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0007097
Disease: Carcinoma
Carcinoma 		0.030 Biomarker group BEFREE Here, we reveal that integrin α(v)β₃ serves as a marker of breast, lung and pancreatic carcinomas with stem-like properties that are highly resistant to receptor tyrosine kinase inhibitors such as erlotinib. 24747441 2014
CUI: C0007097
Disease: Carcinoma
Carcinoma 		0.030 AlteredExpression group BEFREE In conclusion, the expression of ITGAV was significantly correlated with differentiation and metastasis of the laryngeal and hypopharyngeal carcinomas; down-regulation of ITGAV gene could inhibit proliferation of Hep-2 cells and induce to its apoptosis. 18427826 2009
CUI: C0007097
Disease: Carcinoma
Carcinoma 		0.030 AlteredExpression group BEFREE Increased activity of the proto-oncogene c-Src and elevated levels of integrin alpha(v)beta(3) are found in melanomas and multiple carcinomas. 17363590 2007