ITGAX, integrin subunit alpha X, 3687

N. diseases: 170; N. variants: 8
Disease: Mixed cryoglobulinemia ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0543697
Disease: Mixed cryoglobulinemia
Mixed cryoglobulinemia 		0.020 Biomarker disease BEFREE In HCV-associated mixed cryoglobulinemia (MC) there is accumulation of exhausted clonal B cells expressing a V(H)1-69-encoded cross-reactive idiotype; these cells are phenotypically heterogeneous, displaying either a CD21(low)CD11c(+) or a marginal zone (MZ)-like (IgM(+)CD27(+)CD21(+)CD11c(-)) phenotype. 22382878 2012
CUI: C0543697
Disease: Mixed cryoglobulinemia
Mixed cryoglobulinemia 		0.020 Biomarker disease BEFREE Moreover, HCV(+)MC(+) patients' clonal peripheral B cells are enriched with CD21(low), CD11c(+), FCRL4(high), IL-4R(low) memory B cells. 21421840 2011