ITGB3, integrin subunit beta 3, 3690

N. diseases: 260; N. variants: 44
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0699791
Disease: Stomach Carcinoma
Stomach Carcinoma
0.030 Biomarker disease BEFREE The aim of this study was to investigate the role of miR-124- 3p and ITGB3 in gastric cancer. 31836324 2020
CUI: C0699791
Disease: Stomach Carcinoma
Stomach Carcinoma
0.030 Biomarker disease BEFREE Hence, the inhibition of IFN-γ or integrin β3 may be the key for the treatment of gastric cancer. 29306706 2018
CUI: C0699791
Disease: Stomach Carcinoma
Stomach Carcinoma
0.030 AlteredExpression disease BEFREE SP1 directly binds the G9A promoter and enhances G9A expression, and upregulated G9A then forms a transcriptional activator complex with P300 and GR, thereby promoting ITGB3 expression induced by dexamethasone (DEX) and contributing to GC metastasis. 29449539 2018