JAK1, Janus kinase 1, 3716

N. diseases: 239; N. variants: 41
Disease: Adenocarcinoma of pancreas ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0281361
Disease: Adenocarcinoma of pancreas
Adenocarcinoma of pancreas 		0.010 Biomarker disease BEFREE This phase Ib/II dose-optimization study assessed itacitinib, a selective JAK1 inhibitor, combined with <i>nab</i>-paclitaxel plus gemcitabine in adults with treatment-naïve advanced/metastatic disease (Part 1) or pancreatic adenocarcinoma (Parts 2/2A; NCT01858883). 30115734 2019