|
Coronary Artery Disease
|
0.440 |
GeneticVariation
|
disease |
BEFREE |
Aim was to estimate the genotypic distribution and risk allele frequencies of 13 Coronary Artery Disease (CAD) risk Single Nucleotide Polymorphisms in loci identified by the CARDIoGRAMplusC4D consortium namely MIA3 rs17465637; 9p21 rs10757274; CXCL12 rs1746048; APOA5 rs662799; APOB rs1042031; LPA rs3798220; LPA 10455872; MRAS rs9818870; LPL rs328; SORT1 rs646776; PCSK9 rs11591147; APOE rs429358; APOE rs7412 in Pakistani PCAD patients and controls.
|
28705542 |
2019 |
|
Coronary Artery Disease
|
0.440 |
GeneticVariation
|
disease |
GWASCAT |
Identification of 64 Novel Genetic Loci Provides an Expanded View on the Genetic Architecture of Coronary Artery Disease.
|
29212778 |
2018 |
|
Coronary Artery Disease
|
0.440 |
GeneticVariation
|
disease |
GWASCAT |
Efficiently controlling for case-control imbalance and sample relatedness in large-scale genetic association studies.
|
30104761 |
2018 |
|
Coronary Artery Disease
|
0.440 |
GeneticVariation
|
disease |
GWASCAT |
Association analyses based on false discovery rate implicate new loci for coronary artery disease.
|
28714975 |
2017 |
|
Coronary Artery Disease
|
0.440 |
Biomarker
|
disease |
BEFREE |
In this study, we have uncovered a novel molecular network between ADTRP and MIA3/TANGO1 for the pathogenesis of CAD.
|
28341552 |
2017 |
|
Coronary Artery Disease
|
0.440 |
GeneticVariation
|
disease |
GWASCAT |
A comprehensive 1,000 Genomes-based genome-wide association meta-analysis of coronary artery disease.
|
26343387 |
2015 |
|
Coronary Artery Disease
|
0.440 |
GeneticVariation
|
disease |
BEFREE |
We conclude that SNP rs17465637 in MIA3 is indeed a genetic risk factor for CAD across different ethnic populations.
|
24125424 |
2013 |
|
Coronary Artery Disease
|
0.440 |
GeneticVariation
|
disease |
BEFREE |
Genome-wide association studies have described an association between MIA3 rs17465637 A/C polymorphisms and coronary artery disease and myocardial infarction.
|
22577832 |
2012 |
|
Coronary Artery Disease
|
0.440 |
Biomarker
|
disease |
CTD_human |
Large-scale association analysis identifies 13 new susceptibility loci for coronary artery disease.
|
21378990 |
2011 |
|
Myocardial Infarction
|
0.430 |
GeneticVariation
|
disease |
GWASCAT |
A comprehensive 1,000 Genomes-based genome-wide association meta-analysis of coronary artery disease.
|
26343387 |
2015 |
|
Myocardial Infarction
|
0.430 |
GeneticVariation
|
disease |
BEFREE |
Genome-wide association studies have described an association between MIA3 rs17465637 A/C polymorphisms and coronary artery disease and myocardial infarction.
|
22577832 |
2012 |
|
Myocardial Infarction
|
0.430 |
GeneticVariation
|
disease |
BEFREE |
Our results establish two SNPs, rs17465637 in MIA3 and rs599839 near SORT1 as significant risk factors for MI in the American Genebank Caucasian population.
|
21463265 |
2011 |
|
Myocardial Infarction
|
0.430 |
GeneticVariation
|
disease |
BEFREE |
In addition to correspond with such isolated evidence of association with MI, the present study identified specific haplotypes capturing the risk-related variation in the entire MIA3 region.
|
21264445 |
2011 |
|
Myocardial Infarction
|
0.430 |
Biomarker
|
disease |
CTD_human |
Genome-wide association of early-onset myocardial infarction with single nucleotide polymorphisms and copy number variants.
|
19198609 |
2009 |
|
Myocardial Infarction
|
0.430 |
GeneticVariation
|
disease |
GWASCAT |
Genome-wide association of early-onset myocardial infarction with single nucleotide polymorphisms and copy number variants.
|
19198609 |
2009 |
|
Myocardial Infarction
|
0.430 |
GeneticVariation
|
disease |
GWASDB |
Genome-wide association of early-onset myocardial infarction with single nucleotide polymorphisms and copy number variants.
|
19198609 |
2009 |
|
Coronary Arteriosclerosis
|
0.330 |
Biomarker
|
disease |
BEFREE |
Identification of a molecular signaling gene-gene regulatory network between GWAS susceptibility genes ADTRP and MIA3/TANGO1 for coronary artery disease.
|
28341552 |
2017 |
|
Coronary Arteriosclerosis
|
0.330 |
GeneticVariation
|
disease |
BEFREE |
Meta-analysis identifies robust association between SNP rs17465637 in MIA3 on chromosome 1q41 and coronary artery disease.
|
24125424 |
2013 |
|
Coronary Arteriosclerosis
|
0.330 |
GeneticVariation
|
disease |
BEFREE |
Genome-wide association studies have described an association between MIA3 rs17465637 A/C polymorphisms and coronary artery disease and myocardial infarction.
|
22577832 |
2012 |
|
Coronary Arteriosclerosis
|
0.330 |
Biomarker
|
disease |
CTD_human |
Large-scale association analysis identifies 13 new susceptibility loci for coronary artery disease.
|
21378990 |
2011 |
|
Coronary heart disease
|
0.150 |
Biomarker
|
disease |
BEFREE |
Identification of a molecular signaling gene-gene regulatory network between GWAS susceptibility genes ADTRP and MIA3/TANGO1 for coronary artery disease.
|
28341552 |
2017 |
|
Coronary heart disease
|
0.150 |
GeneticVariation
|
disease |
BEFREE |
In the present study, polymorphisms of genes related to CHD (MIA3, MRAS, PCSK9, SMG6, and ZC3HC1) were associated with nondipping SBP and DBP profile, and GRS18 was associated with nondipping status.
|
27189819 |
2016 |
|
Coronary heart disease
|
0.150 |
GeneticVariation
|
disease |
BEFREE |
Meta-analysis identifies robust association between SNP rs17465637 in MIA3 on chromosome 1q41 and coronary artery disease.
|
24125424 |
2013 |
|
Coronary heart disease
|
0.150 |
GeneticVariation
|
disease |
GWASDB |
A genome-wide association study for coronary artery disease identifies a novel susceptibility locus in the major histocompatibility complex.
|
22319020 |
2012 |
|
Coronary heart disease
|
0.150 |
GeneticVariation
|
disease |
BEFREE |
The Ch9p21 SNPs rs1333049 (OR 1.17; 95% confidence limits 1.11-1.24) and rs10757274 (OR 1.17; 1.09-1.26), MIA3 rs17465637 (OR 1.10; 1.04-1.15), Ch2q36 rs2943634 (OR 1.08; 1.03-1.14), APC rs383830 (OR 1.10; 1.02, 1.18), MTHFD1L rs6922269 (OR 1.10; 1.03, 1.16), CXCL12 rs501120 (OR 1.12; 1.04, 1.20), and SMAD3 rs17228212 (OR 1.11; 1.05, 1.17) were all associated with CHD risk, but not with the CHD biomarkers and risk factors measured.
|
21804106 |
2012 |