Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0020538
Disease: Hypertensive disease
Hypertensive disease
0.550 GeneticVariation group BEFREE KCNMB1 gain-of-function variant Glu65Lys results in generalized vasorelaxation and thus protection against systemic hypertension. 20861615 2010
CUI: C0020538
Disease: Hypertensive disease
Hypertensive disease
0.550 AlteredExpression group LHGDN Maxi-K+ channel beta1 expression in sleep apnea patients and its modulation by CPAP treatment. 19057512 2009
CUI: C0020538
Disease: Hypertensive disease
Hypertensive disease
0.550 GeneticVariation group BEFREE We also found that the carriers of minor T allele of KCNMB1-rs11739136 had a significantly decreased risk for hypertension (TT+CT vs. CC; odds ratio=0.83; 95% confidence interval, 0.72-0.95; P value after the Bonferroni correction=0.008 x 5=0.040). 18496125 2008
CUI: C0020538
Disease: Hypertensive disease
Hypertensive disease
0.550 Biomarker group CTD_human KCNMB1 is involved in calcium sensitivity and hypertension. 17700361 2007
CUI: C0020538
Disease: Hypertensive disease
Hypertensive disease
0.550 Biomarker group BEFREE KCNMB1 is involved in calcium sensitivity and hypertension. 17700361 2007
CUI: C0020538
Disease: Hypertensive disease
Hypertensive disease
0.550 Biomarker group RGD Altered expression of BK channel beta1 subunit in vascular tissues from spontaneously hypertensive rats. 16814121 2006
CUI: C0020538
Disease: Hypertensive disease
Hypertensive disease
0.550 Biomarker group BEFREE Association analysis between hypertension and CYBA, CLCNKB, and KCNMB1 functional polymorphisms in the Japanese population--the Suita Study. 15671602 2005
CUI: C0020538
Disease: Hypertensive disease
Hypertensive disease
0.550 Biomarker group RGD Downregulation of the BK channel beta1 subunit in genetic hypertension. 14551242 2003