KDR, kinase insert domain receptor, 3791

N. diseases: 623; N. variants: 23
Disease: Germ cell tumor ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0205851
Disease: Germ cell tumor
Germ cell tumor 		0.020 Biomarker disease BEFREE Next generation sequencing analysis of platinum refractory advanced germ cell tumor sensitive to Sunitinib (Sutent®) a VEGFR2/PDGFRβ/c-kit/ FLT3/RET/CSF1R inhibitor in a phase II trial. 25085632 2014
CUI: C0205851
Disease: Germ cell tumor
Germ cell tumor 		0.020 AlteredExpression disease BEFREE To investigate the molecular mechanisms underlying neovascularization in human germ cell tumors (GCTs), we analysed the expression of two angiogenic growth factors, vascular endothelial growth factor (VEGF) and placenta growth factor (P1GF), and of their receptors (FLT-1) and Flk-1/KDR) in a panel of testicular tumors. 8760299 1996