KISS1, KiSS-1 metastasis suppressor, 3814

N. diseases: 179; N. variants: 15
Disease: Osteosarcoma of bone ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0585442
Disease: Osteosarcoma of bone
Osteosarcoma of bone 		0.040 Biomarker disease BEFREE Our study demonstrated that MNX1-AS1 could enhance osteosarcoma cell proliferation and invasion by inhibiting KISS1, which might contribute to the therapy for osteosarcoma. 31364121 2019
CUI: C0585442
Disease: Osteosarcoma of bone
Osteosarcoma of bone 		0.040 Biomarker disease BEFREE We furthermore identified some relevant core genes using gene-gene interaction network analysis such as EIF4E, FAU, HSPD1, IL-6, and KISS1, which may have a relationship with the development process of OS. 29921292 2018
CUI: C0585442
Disease: Osteosarcoma of bone
Osteosarcoma of bone 		0.040 Biomarker disease BEFREE Based on these results, we showed that KISS-1 inhibited the proliferation of osteosarcoma in vitro, probably by accelerating the processes of apoptosis and autophagy in the cells. 28075440 2017
CUI: C0585442
Disease: Osteosarcoma of bone
Osteosarcoma of bone 		0.040 Biomarker disease BEFREE The osteosarcoma cell lines and specimen sections of osteosarcoma together with control were immuno-stained with KISS1 antibody. 22471458 2011