KLK1, kallikrein 1, 3816

N. diseases: 132; N. variants: 3
Disease: Kidney Failure, Acute ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0022660
Disease: Kidney Failure, Acute
Kidney Failure, Acute 		0.330 AlteredExpression disease BEFREE Quantitative analysis of the activity of one of the identified enzymes, kallikrein-1, revealed some trends suggesting differences in the levels and temporal patterns of enzyme activity between a subset of patients who developed AKI and those who did not. 30192561 2018
CUI: C0022660
Disease: Kidney Failure, Acute
Kidney Failure, Acute 		0.330 GeneticVariation disease BEFREE KLK1 promoter polymorphisms are associated with development of AKI and adverse outcomes. 23635481 2012
CUI: C0022660
Disease: Kidney Failure, Acute
Kidney Failure, Acute 		0.330 Biomarker disease BEFREE Unexpectedly, increased KLK1 excretion in AKI patients was found; this increase is likely to be due in part to increments in adrenergic tone during BP depression. 21679467 2011
CUI: C0022660
Disease: Kidney Failure, Acute
Kidney Failure, Acute 		0.330 Therapeutic disease CTD_human Role of tissue kallikrein in prevention and recovery of gentamicin-induced renal injury. 18227104 2008