KLK1, kallikrein 1, 3816

N. diseases: 132; N. variants: 3
Disease: ovarian neoplasm ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0919267
Disease: ovarian neoplasm
ovarian neoplasm 		0.030 GeneticVariation disease BEFREE Eighty-one chemotherapy naïve serous OCas were examined using 3-colour fluorescence in situ hybridization (FISH) to identify structural and numerical changes on 19q, including the KLK locus; in addition to immunohistochemistry (IHC) for KLK6, which has been shown to be overexpressed in OCa. 20800559 2011
CUI: C0919267
Disease: ovarian neoplasm
ovarian neoplasm 		0.030 Biomarker disease BEFREE The tissue kallikrein (KLK) genes are a new source for biomarkers in ovarian cancer. 19383346 2008
CUI: C0919267
Disease: ovarian neoplasm
ovarian neoplasm 		0.030 Biomarker disease BEFREE However, members of the tissue kallikrein serine protease family, the serine protease uPA and its inhibitor PAI-1, are associated with tumor progression of ovarian cancer. 16895483 2006