KRT8, keratin 8, 3856

N. diseases: 166; N. variants: 16
Disease: Irritable Bowel Syndrome ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0022104
Disease: Irritable Bowel Syndrome
Irritable Bowel Syndrome 		0.020 Biomarker disease BEFREE Cytokeratin 8 (CK8), for the first time, has been shown to mediate corticotropin-releasing factor (CRF)-induced changes in intestinal permeability in animal models of IBS. 29179184 2017
CUI: C0022104
Disease: Irritable Bowel Syndrome
Irritable Bowel Syndrome 		0.020 GeneticVariation disease BEFREE A novel but rare keratin-8 Arg341-to-Cys is identified in IBD patients. 17509943 2007