KRT15, keratin 15, 3866

N. diseases: 39; N. variants: 2
Disease: Alopecia ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0002170
Disease: Alopecia
Alopecia 		0.010 Biomarker disease BEFREE Permanent hair loss in lichen planopilaris (LPP) results from the depletion of keratin 15 (K15+) epithelial stem cells (eSCs) localized in the bulge of hair follicles (HFs) that have lost their physiological immune privilege (IP), were attacked by a cytotoxic CD8+T-cell- driven inflammatory infiltrate, and have undergone apoptosis or pathological epithelial-mesenchymal-transition (EMT). 31774585 2020