Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0011603
Disease: Dermatitis
Dermatitis 		0.010 AlteredExpression disease BEFREE Local depletion of C10orf99 by lentiviral vectors expressing C10orf99 shRNA effectively ameliorated IMQ-induced dermatitis. 29872130 2018
CUI: C0033860
Disease: Psoriasis
Psoriasis 		0.010 Biomarker disease BEFREE Taken together, these results indicate that C10orf99 plays a contributive role in psoriasis pathogenesis and may serve as a new target for psoriasis treatment. 29872130 2018
CUI: C0037284
Disease: Skin lesion
Skin lesion 		0.010 AlteredExpression group BEFREE We showed that C10orf99 protein was significantly up-regulated in psoriatic skin samples from patients and the ortholog gene expression levels were up-regulated in imiquimod (IMQ)-induced psoriasis-like skin lesions in mice. 29872130 2018
CUI: C0026936
Disease: Mycoplasma Infections
Mycoplasma Infections 		0.010 Biomarker group BEFREE AP-57 exhibited broad-spectrum antimicrobial activities against Gram-positive Staphylococcus aureus, Actinomyce, and Fungi Aspergillus niger as well as mycoplasma and lentivirus. 25585381 2015
CUI: C0079731
Disease: B-Cell Lymphomas
B-Cell Lymphomas 		0.010 Biomarker group BEFREE AP-57 also exhibited DNA binding capacity and specific cytotoxic effects against human B-cell lymphoma Raji. 25585381 2015