LAMA3, laminin subunit alpha 3, 3909

N. diseases: 110; N. variants: 86
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0027651
Disease: Neoplasms
Neoplasms
0.030 GeneticVariation group BEFREE Finally, additional CIN-tumor-associated DNA amplifications were identified for EXT1 (8q24.11) and MYC (8q24.12) as well as DNA deletions for MAP2K5 (15q23) and LAMA3 (18q11.2). 17143621 2007
CUI: C0027651
Disease: Neoplasms
Neoplasms
0.030 GeneticVariation group BEFREE Of particular interest, methylation frequencies of LAMA3 helped to distinguish invasive (72%) from noninvasive (12%) tumors. 14973053 2004
CUI: C0027651
Disease: Neoplasms
Neoplasms
0.030 PosttranslationalModification group BEFREE Our results demonstrate epigenetic inactivation of LN5-encoding genes in breast cancers and association of LAMA3 promoter methylation with increased tumor stage and tumor size. 14695139 2003