STMN1, stathmin 1, 3925

N. diseases: 284; N. variants: 1
Disease: Progressive Neoplastic Disease ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0677932
Disease: Progressive Neoplastic Disease
Progressive Neoplastic Disease 		0.010 Biomarker phenotype BEFREE High percentage of CD8<sup>+</sup> tumor-infiltrating cells (TIC) that are PD-1<sup>+</sup>TIM-3<sup>-</sup>LAG-3<sup>-</sup> (% CD8<sup>+</sup>PD-1<sup>+</sup>TIM-3<sup>-</sup>LAG-3<sup>-</sup> TIC) correlated with high levels of T-cell activation and was associated with longer median irPFS and higher irORR. 30670497 2019