LEP, leptin, 3952

N. diseases: 931; N. variants: 15
Disease: Decrease in appetite ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0232462
Disease: Decrease in appetite
Decrease in appetite 		0.030 Biomarker phenotype BEFREE In this study, we evaluated the effects of PPB effect M1 polarization and inflammation and its ability to restore the effects of leptin, such as a decrease in appetite and body weight. 31739649 2019
CUI: C0232462
Disease: Decrease in appetite
Decrease in appetite 		0.030 AlteredExpression phenotype BEFREE Females with increased appetite/weight had higher leptin levels than those with stable or reduced appetite/weight, however males showed the opposite effect. 30071417 2018
CUI: C0232462
Disease: Decrease in appetite
Decrease in appetite 		0.030 Biomarker phenotype BEFREE Leptin is a protein produced by adipose tissue that acts in the central nervous system (CNS) to decrease appetite and increase energy expenditure. 10981165 2000