LEP, leptin, 3952

N. diseases: 931; N. variants: 15
Disease: Convulsive Seizures ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0751494
Disease: Convulsive Seizures
Convulsive Seizures 		0.310 Biomarker phenotype BEFREE The objective of this study is to examine the effects of the endogenous ligands leptin, ghrelin, and neuropeptide Y (NPY) on seizure generation, the oxidant/antioxidant balance, and cytokine levels, which are a result of immune response in a convulsive seizure model. 27522536 2017
CUI: C0751494
Disease: Convulsive Seizures
Convulsive Seizures 		0.310 Therapeutic phenotype CTD_human Leptin-mediated cell survival signaling in hippocampal neurons mediated by JAK STAT3 and mitochondrial stabilization. 17993459 2008